Does tianeptine show up on drug test?
Because the substance does not show up on drug screens, many have found that employment or parole drug tests can be passed even with recent use. Recently, reports of the negative effects of tianeptine sodium use at higher amounts and reports of some people injecting the drug intravenously have begun to surface.
The metabolism of tianeptine is hepatic, via β-oxidation. CYP enzymes are not involved, which limits the potential for drug-drug interactions. Maximal concentration is reached in about an hour and the elimination half-life is 2.5 to 3 hours.
The Tianeptine, also known as “ZaZa Red,” is an antidepressant, and one of the earliest depression treatments, according to the University of Alabama at Birmingham. The Madisonville Police said the drug creates withdrawal similar to heroin and has not been approved by the Federal Drug Administration for use in any way.
Michigan, Georgia, Alabama, and Tennessee banned the sale and manufacturing of Tianeptine between 2018 and 2022. This bottle of Zaza contains Tianeptine. Alabama followed in Michigan's footsteps in 2021. In 2022, Georgia, Tennessee and Ohio took a more severe stance by classifying it as schedule I.
Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants 1.
These novel synthetic opioids include the benzamide-based opioids U-47700 and AH-7921, tianeptine and MT-45. Novel synthetic opioids are amongst the most abundant and potentially lethal new psychoactive substance (NPS) chemical subclass.
It has equivalent antidepressant efficacy to several classical antidepressant agents (amitriptyline, clomipramine, imipramine, mianserin) and the SSRIs fluoxetine (in most patients), paroxetine and sertraline.
Tianeptine is not currently controlled under the Controlled Substances Act.
Pills and powders containing a substance known as tianeptine are being marketed as supplements that claim to provide an "intense mood boost" and "mental clarity." The "supplement," which commonly goes by the brand names ZaZa or Tianna Red, are instead bringing deadly outcomes.
ZaZa Strain Effects
It may make you feel sleepy and calm so it's best not to smoke it if you want to be motivated/creative. In other words, it is a dreamy strain that may be good for someone who has trouble sleeping at night. Additionally, many said smoking this strain made them feel super hungry, happy, and relaxed.
What is the main ingredient in ZaZa?
Tianeptine is known as ZaZa and Tianna Red by users, who were able to find it readily available in gas stations. In their Clinical Toxicology paper, Rushton and colleagues reported on 48 cases of tianeptine toxicity — overdoses and withdrawal — between Jan.
Tianeptine is an unapproved drug in the U.S. Although other countries have approved tianeptine to treat depression and anxiety, some have restricted how tianeptine is prescribed or dispensed, or revised the drug label to warn of possible addiction.
- Amphetamines, such as ecstasy, crystal meth, or Ritalin.
- Phencyclidine, also called PCP or angel dust.
- Cocaine and crack cocaine.
- Opiates, such heroin, oxycodone, or hydrocodone.
- Marijuana.
- Barbiturates.
- Benzodiazepines, such as Xanax and Valium.
- Methadone.
It has equivalent antidepressant efficacy to several classical antidepressant agents (amitriptyline, clomipramine, imipramine, mianserin) and the SSRIs fluoxetine (in most patients), paroxetine and sertraline.
Tianeptine is a prescription drug used for depression in some European, Asian, and Latin American countries. It is not approved for use in the US. Tianeptine affects brain chemicals. It seems to affect mood when used in low doses.